Hippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis
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چکیده
منابع مشابه
Hippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis
BACKGROUND Emerging data have demonstrated that peroxisome proliferator-activated receptor δ (PPARδ) activation confers a potentially neuroprotective role in some neurodegenerative diseases. However, whether PPARδ is involved in depression is unknown. METHODS In this study, PPARδ was firstly investigated in the chronic mild stress (CMS) and learned helplessness (LH) models of depression. The ...
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ژورنال
عنوان ژورنال: International Journal of Neuropsychopharmacology
سال: 2015
ISSN: 1461-1457,1469-5111
DOI: 10.1093/ijnp/pyv083